LTB4 Is a Signal-Relay Molecule during Neutrophil Chemotaxis
نویسندگان
چکیده
منابع مشابه
Exosomes Mediate LTB4 Release during Neutrophil Chemotaxis
Leukotriene B4 (LTB4) is secreted by chemotactic neutrophils, forming a secondary gradient that amplifies the reach of primary chemoattractants. This strategy increases the recruitment range for neutrophils and is important during inflammation. Here, we show that LTB4 and its synthesizing enzymes localize to intracellular multivesicular bodies that, upon stimulation, release their content as ex...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2012
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2012.02.003